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Who are you calling ‘anti-science’? How science serves social and political agendas

The Conversation

File 20170713 19681 1ey4qzl
Left, right, populist, elitist: there are many different ways to be anti-science. arindambanerjee/shutterstock

Darrin Durant, University of Melbourne

Florida recently passed a law which “authorizes county residents to challenge use or adoption of instructional materials” in schools. It’s been described as “anti-science” by individual scientists and USA’s National Center for Science Education.

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From climate change to vaccination, genetic modification and energy security, anti-science is used as a critical phrase implying a person or group is rejecting science outright.

But it’s not that simple.

All shades of political positions are routinely ambivalent about science. Neither the right or left arms of politics are consistent supporters or attackers of science.


Read more: Why politicians think they know better than scientists


If there is no one definition of anti-science that works across all settings, why does it matter that we know anti-science means different things to different people? The reason is that science remains a key resource in arguing for social and political change or non-change.

Knowing what counts as anti-science for distinct groups can help illuminate what people take to be the proper grounds for social and political decision-making.

Left, right, populist, elitist

First up, I’ll define some broad terms.

To be politically “left” is to be concerned about social and economic equality, sometimes cultural equality too, and usually a state big enough to protect the less fortunate and less powerful.

To be “right” is to be concerned about individual autonomy and a state small enough to let markets and personal responsibility decide fates rather than central planners.

To be “populist” involves being anti-elite, anti-pluralist (the “us vs them” view of civic relations), tending toward conspiracy theories, and displaying a preference for direct over representative democracy.

It’s also worth noting here that science can be viewed as an elite endeavour. Not elitist in the two main negative senses, of being impractical or of being practiced by special people somehow different in kind to the rest of us. Instead, I mean science is elitist in the more technical sense of being a professionalised body of practice.

To become a scientist is to be admitted to an elite group in society – not everyone can attend events like Science and Technology 2017 Conference held in Hofburg Palace, Austria. ctbto/flickr, CC BY

The skills and knowledge possessed by scientists are gained by social immersion in various forms of training regimens. Both those learning contexts and the resulting skills and knowledge gained are not widely participated in, nor widely distributed. The experience-based and often professionalised context of science creates a select group.

Different flavours of anti-science

To make clear the way anti-science comes in different political flavours, let me first make some general claims.

Populists of either left-wing or right-wing persuasions distrust elites, and that can be enough for populists to at least be suspicious of factual claims produced distant from the populist. Pauline Hanson said that public vaccinations are a worry and parents should do their own research, including getting a (non-existent) test of their child for negative effects.

Anti-science among the mainstream left and right wings of politics is more complex. Each share a worry that science can be corrupted, but the left blames capitalist profiteering, and the right blames careerist attempts to distort the market.

Each also shares a worry that science can engulf politics, but the left worries that technical answers will displace deliberative politics, and the right worries that science will displace traditional values as the motor of social change.

But whereas anti-science from the left arises as a label for apprehensions about the application of science, anti-science from the right arises as a label for apprehensions about science’s raw ability to discover causal connections.

Populist left

Skeptic magazine publisher Michael Shermer thinks the populist left are anti-science by virtue of disliking genetically modified organisms (GMOs), nuclear power, fracking and vaccines. According to him, they shockingly obsess over the “purity and sanctity of air, water and especially food”.

But writer Chris Mooney is correct to reply that, taking vaccine-related scepticism as an example, Shermer has picked up on conspiracist rather than leftist beliefs.

Lacking authoritarianism, today’s populist-left disquiet with science is actually a lament that production-science tramples human values.

An example might be the Australian Vaccination Network, which claims to be neither pro- nor anti-vaccination and instead “pro-choice”. The populist left in this case pushes parental rights to the limit, presenting it as sufficient for decision-making yet under threat by larger institutions and their “foreign” ways.

Mainstream left

The mainstream-left are more ambivalent than straight anti-anything. GMOs and nuclear power are suspect? Climate science and vaccinations are promising? Leftist anti-science is more about anti-corruption and wariness that technical reasoning will supplant values debates in our democracies.

Greenpeace believes some kinds of scientific evidence, but distrusts others. takver/flickr, CC BY-SA

The Greenpeace critique of GMOs is a good example. Greenpeace appeals for independent science but suggests agro-chemical corporations are corrupting it, and they call for ethical-political deliberation about our food supply not just dry technical assessments of safety.

Populist right

The populist-right implies shadow governments conspire against the market and the people, as when the One Nation senator Malcolm Roberts reportedly claimed climate change science had been captured by “some of the major banking families in the world” who form a “tight-knit cabal”.

In general, the populist-right’s anti-science is just pro-conspiracist.

Mainstream right (small-state conservatives)

The mainstream-right is more complicated.

Sociologist Gordon Gauchat found that to be anti-science the political right had to score high on four dimensions:

  • religiosity
  • authoritarianism
  • distrust of government, and
  • scientific literacy (surprisingly).

They sometimes parrot the left’s allegations of corruption, but mainstream-right and populist-right approach corruption differently.

The mainstream-right is loath to imply a shadow world order, as that disrupts the ideology of the market. Instead, they limit the corruption implication to accusations of groupthink that distort the market (the typical example being climate scientists shutting down dissent for careerist reasons).

The mainstream-right has bigger fish to fry. Philosopher Heather Douglas has ideas about why the political right leans toward anti-science.

Douglas argues that shifts in the public-private boundary, whereby private behaviours become treated as matters of public concern, trouble the right more than the left. Social change is thus viewed more positively by progressive leftists than traditionalist right-wingers.

Douglas suggests that science routinely discovers causal relationships that prompt shifts in the public-private boundary; like finding waste has human and biosphere effects beyond the individual. That means science is pitted directly against traditional values as one of the motors of social change.

Not every example fits Douglas’ pattern. The Australian Liberal Party has been described as undermining renewable energy and being resistant to meaningful policy action on climate change, but clearly supports vaccination. Is that because, for the right, vaccinations expand the market, and right-wingers are more comfortable with social change driven by markets?

The predatory influence science can exert over important ethical-political issues troubles both left and right-wingers.

But where the left worries about the application of science to broader issues, small-state conservatives implicitly react to the means of production that enable political application: the discovery of causal relationships. The observations and experiments that feed into community-based assessments of causality constitute the core of science, not its secondary application to social issues.

As regulatory science has grown since the 1950s, small-state conservatives watched it expand the state by showing the private could be public. Science is a well-resourced competitor among the motors of social change.

Small-state conservatives experience science as guiding social change, a function they want to preserve for traditional values. Small-state conservatives are the true heirs to anti-science.

When the historian Naomi Oreskes talks of merchants of doubt – right-wing free marketers opposed to environmental regulation – she is in my judgement talking about small-state conservatives worried that science is a motor of change outside their sphere of direct control.

What anti-science isn’t, and what it might be

In his book How to be Antiscientific, Steven Shapin argues that descriptions of science, and what ought to be done in science, vary tremendously among scientists themselves.

So you’re not anti-science if you have a preference for or against things like a preferred method, or some particular philosophy of science, or some supposed “character” of science.

Nor are you anti-science because you highlight the uncertainties, the unknowns and the conditionality of scientific knowledge. Even when you are the outsider to science. That’s called free speech in a democracy.

Where does that leave anti-science? Maybe it leaves anti-science living with small-state conservatives, who in effect cast aspersions about something that might be essential to the ideal of scientific authority having a positive and functional relationship with democracy. That is, science as a public good.

If you end up denying the relevance of science to informing or guiding democratic decision-making, because you want some value untouched by information to do that guidance work, maybe that makes you about as anti-scientific as democracies can tolerate.


The ConversationRead more: Should scientists engage with pseudo-science or anti-science?


Darrin Durant, Lecturer in Science and Technology Studies, University of Melbourne

This article was originally published on The Conversation. (Reblogged by permission). Read the original article.

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DNA and GM foods

by Tim Harding B.Sc

(An edited version of this essay was published in The Skeptic magazine, September 2014, Vol 34 No 3, under the title ‘The Good Oil’.  The essay is based on a talk presented to the Mordi Skeptics, Tuesday 5 April 2011; and later to the Sydney Skepticamp, 30th April 2011.)

In May 2014, a farmer accused of ‘contaminating’ his neighbour’s land with genetically modified canola won a highly publicised civil case in the Western Australian Supreme Court (Marsh v. Baxter, 2014).  Although the case was about a claim of conflicting land use rather than food safety, it fired up the long-running community debate about genetically modified foods in Australia.  It also exposed a lot of misinformation and misunderstanding about DNA and genetic modification.

This essay discusses the nature and structure of DNA; together with the history of its discovery. It makes the point that artificial selection been occurring since the dawn of civilisation; and that the outcome of different methods of artificial selection is the same – modification of the genetic code by human intervention. Not only is there no evidence that genetically modified foods are unsafe to eat, but there is no mechanism by which they could be unsafe.

Brief history of DNA research

The rules of genetics were largely understood since Gregor Mendel’s ‘wrinkled pea’ experiments in the 1860s but the mechanisms of inheritance remained a mystery.   Charles Darwin knew in the 1850s there must have been such a mechanism (but his later speculations about it – called pangenesis – were wrong).[1]  The units of inheritance were called genes, but it was not understood where genes were located in the body or what they physically consisted of.

After the rediscovery of Mendel’s work in the 1890s, scientists tried to determine which molecules in the cell were responsible for inheritance.  In 1910, Thomas Hunt Morgan argued that genes are on chromosomes, based on observations of a sex-linked white eye mutation in fruit flies.  In 1913, his student Alfred Sturtevant used the phenomenon of genetic linkage to show that genes are arranged linearly on the chromosome.  It was soon discovered that chromosomes consisted of DNA and proteins, but DNA was not identified as the gene carrier until 1944.

Watson and Crick’s breakthrough discovery of the chemical structure of DNA in 1953 finally revealed how genetic instructions are stored inside organisms and passed from generation to generation.[2]  In the following years, scientists tried to understand how DNA controls the process of protein production. It was discovered that the cell uses DNA as a template to create matching messenger RNA (a single-strand molecule with nucleotides, very similar to DNA). The nucleotide sequence of a messenger RNA is used to create an amino acid sequence in protein; this translation between nucleotide and amino acid sequences is known as the genetic code.

DNA structure

The molecular basis for genes is deoxyribonucleic acid (DNA) a double-stranded molecule, coiled into the shape of a double-helix.  DNA is composed of twin backbones of sugars and phosphate groups joined by ester bonds.  These backbones hold together a chain of nucleotides, of which there are four types: adenine (A), cytosine (C), guanine (G), and thymine (T).  Genetic information in all living things exists in the sequence of these nucleotides, and genes exist as stretches of sequence along the DNA chain.[3]  Each nucleotide in DNA preferentially pairs with its partner nucleotide on the opposite strand: A pairs with T, and C pairs with G using weak hydrogen bonds.  Thus, in its two-stranded form, each strand effectively contains all necessary information, redundant with its anti-parallel partner strand.  This structure of DNA is the physical basis for inheritance: DNA replication duplicates the genetic information by enzymes splitting the strands (like a zipper) and using each strand as a template for synthesis of a new partner strand.

Chemical structure of DNA (Source: Wikimedia Commons)

Chemical structure of DNA (Source: Wikimedia Commons)

The sequence of these nucleotides A, C, G and T is a code, similar to the binary digital code used in computing.  When you consider that all the instructions for everything that computers can produce: text, calculations, music and images is stored as a binary sequence of ones and zeros, it is not hard to conceive how the instructions for making and operating living organisms can be stored as a four letter code.

Genes are arranged linearly along very long chains of DNA sequence, which comprise the chromosomes.  In bacteria, each cell usually contains a single circular chromosome, while eukaryotic organisms (including plants and animals) have their DNA arranged in multiple linear chromosomes.  These DNA strands are often extremely long; the largest human chromosome (No. 1), for example, is about 247 million base pairs in length. The full set of hereditary material in an organism (usually the combined DNA sequences of all 46 chromosomes in humans) is called the genome (approx. 3 billion base pairs in humans).

The genetic code is the set of rules by which information encoded in genetic material (DNA or mRNA sequences) is translated into proteins (amino acid sequences) by living cells.  The code defines a mapping between tri-nucleotide sequences, called codons, and amino acids. With some exceptions, a triplet codon in a nucleic acid sequence specifies a single amino acid.[4]

Translation of genetic code into proteins (Source: Wikimedia Commons)

Translation of genetic code into proteins (Source: Wikimedia Commons)

However, the human genome contains only ca. 23,000 protein-coding genes, far fewer than had been expected before its sequencing.  In fact, only about 1.5% of the genome codes for proteins, while the rest consists of non-coding RNA genes, regulatory sequences, introns, and noncoding DNA (once known as ‘junk DNA’). Genetic recombination during sexual reproduction involves the breaking and rejoining of two chromosomes (one from each parent) to produce two new rearranged chromosomes, thus providing genetic diversity and increasing the efficiency of natural selection.

Genetic modification

One of the biggest public misunderstandings is about the very term ‘genetic modification’.  Genes can be modified in 2 main ways:

Artificial selection can occur in 4 main ways:

  • traditional plant and animal breeding (long-term);
  • mutagenesis (random exposure to chemical or radiological mutagens);
  • RNA interference (switching genes on or off);
  • genetic engineering (short-term) – the targeted insertion or deletion of genes in the laboratory (which cannot easily be achieved by other methods).

The end result of the different methods of artificial selection is the same – modification of the genetic code by human intervention.  All DNA, whether modified naturally or artificially, is biochemically and nutritionally the same.  The only difference is in the genetic code, that is, the sequence of the bases G, C, T and A.  In other words, DNA is DNA – there are no such thing as ‘natural DNA’ and ‘artificial DNA’.

They are all ways of artificially modifying genes, yet for some illogical reason plant and animal breeding is not usually referred to in the media as genetic modification – possibly because it started a long time (c. 11,000 years ago) before genetics was understood.  However, to avoid any confusion, in this paper I will refer to genetic modification of foods by genetic engineering as genetically engineered foods (GE foods).

As a result of artificial selection, all farmed foods we eat today have been genetically modified by humans via plant and animal breeding.  This includes all meats except for wild game and kangaroo; and most farmed fish such as salmon.

Similarly all plants we eat (vegetables, fruits,  nuts, herbs and spices) have been genetically modified by humans.  Many varieties bear little resemblance to their original wild forms.  A wheat grain is a genetically modified grass seed.  Can anybody think of a plant food that has not been modified by humans?  (The only ones any of us at the meetup could think of were bush tucker, which is rarely found in Australian shops or supermarkets.  Seaweed was later suggested at the Sydney Skepticamp).

Whenever we eat and digest proteinaceous food, the DNA inside the food gets broken down into single nucleotides before absorption in the small intestine, destroying the genetic code anyway.  It is therefore logically impossible for any changes in the genetic code, whether artificial or natural, to make DNA unsafe to eat.

Not only is it logically impossible, but there is no empirical evidence that genetically modified foods are harmful.  The technology to produce genetically engineered (GE) plants is now over 30 years old, yet in all that time there has not been a single instance of anybody becoming ill, let alone dying, as a result of eating GE foods.

In a recent major review of the scientific literature on last 10 years of the world’s GE crop safety research, the reviewers conclude that ‘the scientific research conducted so far has not detected any significant hazard directly connected with the use of GE crops’.  The authors further believe that ‘genetic engineering and GE crops should be considered important options in the efforts towards sustainable agricultural production’ (Nicolia et al, 2013).

GE foods

GE foods can be produced by either cisgenesis (within the same species) or transgenesis (from different species).[5]  However, the point needs to be made that the human genome naturally contains genes resulting from billions of years of evolution – even genes from our fishy ancestors.  A substantial fraction of human genes seem to be shared among most known vertebrates.  For example, the published chimpanzee genome differs from that of the human genome by 1.23% in direct sequence comparisons.  We also share many genes with plants.

“The real question here is not whether there is a GMO tomato with a fish gene, but who cares? It’s not as if eating fish genes is inherently risky—people eat actual fish. Furthermore, by some estimates people share about 70 percent of their genes with fish. You have fish genes, and every plant you have ever eaten has fish genes; get over it.”[6]

GE foods were first put on the market in the early 1990s.  Typically, genetically modified foods are transgenic plant products: soybean, corn, canola, and cotton seed oil.  

GE genes may be present in whole foods, such as wheat, soybeans, maize and tomatoes.  The first commercially grown genetically modified whole food crop was a tomato (called FlavrSavr), which was modified to ripen without softening, in 1994.  These GE whole foods are not presently available in Australia.  GE food ingredients are, however, present in some Australian foods.  For example, soy flour in bread may have come from imported GE soybeans.[7]

In addition, various genetically engineered micro-organisms are routinely used as sources of enzymes for the manufacture of a variety of processed foods. These include alpha-amylase from bacteria, which converts starch to simple sugars, chymosin from bacteria or fungi that clots milk protein for cheese making, and pectinesterase from fungi which improves fruit juice clarity.

sugar

Genetic engineering can also be used to increase the amount of particular nutrients (like vitamins) in food crops. Research into this technique, sometimes called ‘nutritional enhancement’, is now at an advanced stage. For example, GE golden rice is an example of a white rice crop that has had the vitamin A gene from a daffodil plant inserted. This changes the colour and the vitamin level for countries where vitamin A deficiency is prevalent. Researchers are especially looking at major health problems like iron deficiency. The removal of the proteins that cause allergies from nuts (such as peanuts and Brazil nuts) is also being researched.[8]

Animal products have also been developed, although as of July 2010 none are currently on the market.  However, human insulin has been produced using GE E.coli bacteria since 1978.  In 2006 a pig was controversially engineered to produce omega-3 fatty acids through the expression of a roundworm gene.  Researchers have also developed a genetically-modified breed of pigs that are able to absorb plant phosphorus more efficiently, and as a consequence the phosphorus content of their manure is reduced by as much as 60%.

Once again, there is no evidence of any person being harmed by eating genetically engineered foods.  The reasons why genetically engineered whole foods are not yet available in Australia are political or emotional rather than scientific.

Benefits of GE foods

There is a need to produce inexpensive, safe and nutritious foods to help feed the world’s growing population. Genetic engineering may provide:

  • Sturdy plants able to withstand weather extremes (such drought);
  • Better quality food crops;
  • Higher nutritional yields in crops;
  • Inexpensive and nutritious food, like carrots with more antioxidants;
  • Foods with a greater shelf life, like tomatoes that taste better and last longer;
  • Food with medicinal (nutraceutical) benefits, such as edible vaccines – for example, bananas with bacterial or rotavirus antigens;
  • Crops resistant to disease and insects and produce that requires less chemical application, such as pesticide and herbicide resistant plants: for example, GE canola.[8]

Objections to GE foods

So why is there such significant opposition to GE foods from some vocal lobby groups? Critics have objected to GE foods on several grounds, including:

  • the appeal to nature fallacy (natural products are good and artificial products are bad);
  • alleged but unproven safety issues, (there is no evidence of any adverse health effects, including allergies, in the 20 years since GE foods became available);
  • marketing concerns about ‘contamination’ of so-called organic food crops by GMOs (such as in the Marsh -v-Baxter case);
  • ecological concerns about the spread of GMOs in the wild, and
  • economic or ideological concerns raised by the fact that these organisms are subject to intellectual property rights usually held by big businesses.

The only one of these objections that may have any scientific legitimacy is the ecological concern about the spread of GMOs in the wild.  However, the use of GE technology is highly regulated by Australian governments and any such ecological concerns are fully taken into account.

Current food regulations in Australia state that a GE food will only be approved for sale if it is safe and is as nutritious as its conventional counterparts.  Food regulatory authorities require that GE foods receive individual pre-market safety assessments prior to use in foods for human consumption.  The principle of ‘substantial equivalence’ is also used.  This means that an existing food is compared with its genetically modified counterpart to find any differences between the existing food and the new product.  An important to note is that Australia has the most rigorous food safety testing regime in the world, and that GE foods are tested even more rigorously than non-GE foods. Because of this higher level of testing, GE foods are likely to be safer than non-GE foods.

Foods certified as organic or biodynamic should not contain any GE ingredients, according to voluntary organic food industry guidelines.

Here is a list of 114 peer-reviewed articles and meta reviews, mostly published in moderate to high impact factor journals that support the safety of GMO crops over a wide range of hypotheses.  The consensus position of the American Association for the Advancement of Sciences on GM foods is:

“Indeed, the science is quite clear: crop improvement by the modern molecular techniques of biotechnology is safe… The World Health Organization, the American Medical Association, the U.S. National Academy of Sciences, the British Royal Society, and every other respected organization that has examined the evidence has come to the same conclusion: consuming foods containing ingredients derived from GM crops is no riskier than consuming the same foods containing ingredients from crop plants modified by conventional plant improvement techniques.”

References

American Association for the Advancement Of Science (2012). Statement by the AAAS Board of Directors On Labeling of Genetically Modified Foods. 20 October 2012.

Better Health Channel (2011) Fact Sheet – Genetically modified foods www.betterhealth.vic.gov.au Melbourne: State of Victoria.

Darwin, Charles (1868),The Variation of Animals and Plants under Domestication (1st ed.), London: John Murray.

Lynas, Mark (29 April 2013) Time to call out the anti-GMO conspiracy theory.  Mark Lynas speech hosted by the International Programs – College of Agriculture and Life Sciences (50th Anniversary Celebration) , and the Atkinson Center for a Sustainable Future, Cornell University.

Marsh -v-Baxter [2014] WASC 187 (28 May 2014).

Nocolia, A., Mazo, A., Veronesi, F., and Rosellini (2013) ‘An overview of the last 10 years of the genetically engineered crop safety research’. Critical Reviews in Biotechnology. Informa Healthcare USA Inc. ISSN: 0738-8552 (print) 1549-7801 (electronic).

Skeptical Raptor’s Blog. What does science say about GMO’s–they’re safe. Updated 19 November 2014.

Novella, Stephen (2014) ‘No Health Risks from GMOs’. The Science of Medicine .Volume 38.4, July/August 2014.

Watson J.D. and Crick F.H.C. (1953) A Structure for Deoxyribose Nucleic Acid. Nature 171 (4356): 737–738.

Other information is from Wikipedia and the author’s knowledge as a former biochemist.  (According to convention, anonymous Wikipedia pages, whilst thought to be mostly factually correct, are not citable as references).


[1] Darwin, 1868.

[2] Watson and Crick, 1953.

[3] Viruses are the only exception to this rule—sometimes viruses use the very similar molecule RNA instead of DNA as their genetic material.

[4] Not all genetic information is stored using the genetic code. All organisms’ DNA contains regulatory sequences, intergenic segments, and chromosomal structural areas that can contribute greatly to phenotype by controlling how the genes are expressed.  Those elements operate under sets of rules that are distinct from the codon-to-amino acid paradigm underlying the genetic code.

[5] For example, the gene from a fish that lives in very cold seas has been inserted into a strawberry, allowing the fruit to be frost-tolerant.  However, this has not as yet been done for currently available commercial food crops.

[6] Novella, 2014.

[7] Better Health Channel, 2011.

[8] Better Health Channel, 2011.

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