Tag Archives: vitamin C

Science or Snake Oil: will horseradish and garlic really ease a cold?

The Conversation

File 20171123 6013 1vm5e9b.jpg?ixlib=rb 1.1
Horseradish hasn’t been studied, and studies on garlic found it probably does nothing. from http://www.shutterstock.com

Ken Harvey, Monash University

Some of us may have heard that horseradish and garlic supplements help ease cold and flu. Blooms High Strength Horseradish and Garlic Complex claims it has

a soothing antimicrobial action that helps fight off the bugs that can cause colds and flu and provides symptomatic relief from upper respiratory tract infections.

Others, such as those promoted by Swisse and Blackmores, claim to be “traditionally used in Western Herbal Medicine to provide symptomatic relief of sinusitis, hay fever and upper respiratory tract infections”. And the Swisse and Blackmores products (and many others) add additional ingredients, commonly vitamin C, which is claimed to be beneficial for “immune health”.

There are two categories of “evidence” allowed by the Therapeutic Goods Administration (TGA) to validate indications or claims made for complementary medicines: scientific or traditional.

Scientific evidence is based on the scientific literature, such as trials in humans. Traditional evidence is based on theories outside modern conventional medicine, such as Western herbal medicine, traditional Chinese medicine and homeopathy.


Read more – Science or Snake Oil: can turmeric really shrink tumours, reduce pain and kill bacteria?


So, what does the research say?

A search of the medical journal database PubMed failed to find any clinical trials on the combination of horseradish (Armoracia rusticana) and garlic (Allium sativum), with or without vitamin C. Nor were any clinical trials found on horseradish alone.

The authors of a 2014 Cochrane review concluded there was insufficient clinical trial evidence supporting garlic in preventing or treating the common cold. A single 2001 trial (from the Garlic Centre in the UK) suggested garlic may prevent the common cold, but more studies were needed to validate this finding. Claims of effectiveness appear to rely largely on poor-quality evidence.

A 2013 Cochrane systematic review explored whether taking vitamin C (0.2g a day or more) reduced the incidence, duration or severity of the common cold. The 29 trial comparisons involving 11,306 participants found taking vitamin C regularly failed to reduce the incidence of colds in the general population.

Supplements can claim they’re a traditional medicine, meaning they don’t have to prove they’re effective. Screenshot, Author provided

Regular supplementation had a modest effect in reducing the duration of common cold symptoms by a few hours. The practical relevance of this finding is uncertain. The authors felt this level of benefit did not justify long-term supplementation. Finally, taking vitamin C at the onset of cold symptoms was not effective.

Vitamin C deficiency can impair immune function, but this is uncommon in Australia and best prevented by eating fruit and vegetables.


Read more – Monday’s medical myth: vitamin C prevents colds


The TGA accepts a traditional indication if that use has been recorded in internationally recognised traditional sources for a period of use that exceeds three generations (75 years). Traditional indications or claims don’t mean a product actually works – that requires scientific evidence.

What’s the verdict?

Products such as Blooms High Strength Horseradish & Garlic Complex claim they fight off bugs, but those claims that lack scientific validation. This breaches many provisions of the Therapeutic Goods Advertising Code 2015.

Products such as Swisse Ultiboost High Strength Horseradish + Garlic + Vitamin C, claiming horseradish and garlic have been “traditionally used in Western Herbal Medicine”, have correctly invoked the TGA’s “traditional paradigm”. But it’s important to remember this doesn’t mean these products work.

What’s the implication?

Recently, more and more purveyors of complementary medicine have been making “traditional” claims for their products.

If consumers are to make an informed choice about medicines claiming traditional use, a mandatory statement is required on the label and on all promotion explaining what this means. It should be explained to consumers the “tradition” is not in accordance with modern medical knowledge, and there is no scientific evidence the product works.

Without such a disclaimer, consumers will be misled and the TGA will be seen to be endorsing pseudoscience. But to date, industry, the TGA and government have refused to take on-board such proposals.


The ConversationRead more: Which supplements work? New labels may help separate the wheat from the chaff


Ken Harvey, Associate Professor, School of Public Health and Preventive Medicine, Monash University

This article was originally published on The Conversation. (Reblogged by permission). Read the original article.

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Explainer: what is scurvy and is it making a comeback?>

The Conversation

Karen Charlton, University of Wollongong

A major hospital in western Sydney recently reported a number of diabetes patients were suffering from scurvy, a historical disease common in sailors on long voyages who were deprived of citrus fruit and vegetables.

Scurvy is caused by severe and chronic deficiency of vitamin C (ascorbic acid), and is in modern times extremely rare. But considering our current dietary habits and their association with lifestyle diseases such as diabetes, could scurvy be making a comeback?

What is it?

In 1747, before the protective effects of vitamin C had been identified, British physician James Lind conducted the first clinical experiment in the history of medicine. He provided oranges and lemons to a group of sailors who were showing symptoms of scurvy. They showed remarkable improvements in a short time.

British doctor James Lind conducted an interesting historical experiment. Wikimedia Commons

However, it took more than 50 years for this evidence to be used in practice, and for the British navy to issue lemon juice to sailors.

Vitamin C is necessary for the production of collagen – a vital, structural protein in connective tissues throughout our body – and iron absorption. Because humans can’t naturally make vitamin C, it has to be provided from external sources – either fruits and vegetables or foods fortified with it.

A lack of vitamin C results in a defective formation of collagen and connective tissues, which can result in easy bruising, bleeding gums, blood spots in the skin, joint pain and delayed wound healing.

Because vitamin C is needed for iron absorption, anaemia – which is a lack in the number and quality of red blood cells that carry oxygen – and fatigue may be present in those who are deficient. A blood test to determine vitamin C levels is used to confirm a scurvy diagnosis.

Is it coming back?

The recently reported cases of scurvy reflect poor-quality diets that don’t include sufficient fruit and vegetables. Half of Australians aged over 18 meet the recommended guidelines of eating two or more daily serves of fruit.

Only 7% of the population meet the guidelines for vegetables – five to six or more servings for men depending on age, and five or more for women. Only one in 20 (5.1%) adults meet both.

The situation is not limited to Australia. In the United Kingdom, it has been claimed wartime diseases such as scurvy are being seen in children because of diets high in junk food, which are worse for them than rationing was 70 years ago.

Kiwi fruit and strawberries are two excellent sources of vitamin C. from shutterstock.com

An estimated 25% of British men and 16% of women on low incomes have blood vitamin C concentrations indicative of deficiency, and a further fifth of the population have levels in the depleted range. This is due, in part, to inadequate access to fresh fruit and vegetables. Similar patterns are being identified in the United States.

Some people are more at risk of scurvy than others. Those at high risk are usually elderly people who may have difficulty chewing vitamin C-rich foods, and those with a diet devoid of fresh fruits and vegetables due to low incomes, ignorance or excessively restrictive diets, for example as a result of allergies.

It is estimated that up to 50% of older adults may have a marginal or even deficient vitamin C status. This is especially true for those who live for long periods in institutions such as hospitals, and rely on in-house food for their nutrient requirements.

It’s common practice in hospital kitchens to cook vegetables for prolonged times, which reduces their vitamin C content. Hospitals also often use the cook-to-chill food service system, and vitamin C is lost from food during chilled storage after cooking. Further, patients may dislike hospital food or feel too unwell to eat enough.

Smokers are also at an increased risk of scurvy because smoking decreases concentrations of Vitamin C in the blood by up to 40%.

How can scurvy be prevented?

Scurvy can be prevented by consuming enough vitamin C, either in the diet or as a vitamin supplement. Citrus fruits such as oranges and lemons, as well as kiwi fruit, strawberries, guava, papaya and blackcurrants, are excellent sources. Vegetables high in vitamin C include capsicum, broccoli, potatoes, cabbage, tomatoes, and spinach.

Cooking vegetables for too long can reduce their vitamin C content. from shutterstock.com

One of the western Sydney patients diagnosed with scurvy was reported to cook her vegetables for so long that they would “disintegrate to the touch”.

Overcooking vegetables is likely to destroy vitamin C content. This is due partly to a reaction with oxygen that renders the vitamin inactive, and partly to leaching of the vitamin into the water used for cooking. It has been shown that 10% of the vitamin C content of cabbage was lost by heat-associated destruction during cooking, while 80% was leached into the cooking water.

When cooking vegetables, don’t drop them into the water until it’s boiled. This is because rapidly boiling water contains less oxygen than cold water, and the reaction with oxygen kills off the vitamin’s protective qualities.

Losses during cooking can be reduced by at least half if vegetables are only one-quarter covered by water, rather than being completely immersed. Use of the vegetable cooking water in soups and gravies would also substantially increase the amount of vitamin C you get.

Substantial losses of vitamin C also occur during reheating of chilled food. However, the losses are dependent on the time taken to reheat, as well as the portion size of the foods. Reheating a bulk portion (2kg) of food results in an average vitamin C loss of 23%, compared with losses of 10 to 15% if individually portioned food is reheated for the same length of time.

The re-emergence of scurvy is a poor reflection on the nation’s diet. So eat more fruits and vegetables, and make sure the latter aren’t overcooked.

The ConversationKaren Charlton, Associate Professor, School of Medicine, University of Wollongong

This article was originally published on The Conversation. (Reblogged by permission). Read the original article.

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